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Nanomedicine is a relatively new field of science and technology. “Nanomedicine” is the science and technology of diagnosing, treating, and preventing disease and traumatic injury, using nanoscale structured materials, drug delivery for cancer treatment by enhancing build-ups of cytotoxicity in tumor tissue, specificity in tumor targeting, reducing the cytotoxic side effects on normal cells, reducing systemic side effect, increasing drug solubility, and increasing maximum tolerated dose, of relieving pain, and of preserving and improving human health, biotechnology, genetic engineering and eventually complex machine systems and nonorobots.
Calcium carbonate nanoparticles/ Nanocalcite properties is highly porous, large surface area, high loading capacity, biocompatible, biodegradable, , pH-dependent drug release, stimuli-responsive properties, it an excellent candidate for loading and controlled release of various drugs. Calcium carbonate nanoparticles/ Nanocalcite is highly porous, has a large surface area which confer a high loading capacity.
Recently, there has been widespread interest in their application as drug delivery systems for different groups of drugs. Among them, CaCO3 nanoparticles have exhibited promising potential as drug carriers targeting cancer tissues and cells. calcium carbonate nanoparticles have been observed to be biocompatible for use in medicine, pharmaceutical industries and drug delivery systems.
High biocompatibility- CaCO3 is also employed in many pharmaceutical (anti-acid, dietary supplement for child and postmenopausal women), biological (scaffolds for cellular and bacterial growth) and biomedical (bioactive material for drug delivery, base for orthodontic cements) applications.
CaCO3 nanoparticles have attracted an interest among researchers nowadays especially for therapeutic applications.
Calcium carbonate based material present the biodegradability and biocompatibility properties which is ideal as a smart carrier to deliver genes, enzymes, and drugs.
Calcium carbonate nanoparticles have been observed to be biocompatible for use in medicine, pharmaceutical industries and drug delivery systems
Calcium carbonate use is contraindicated in cases of hypersensitivity, renal calculus, high urine calcium levels, elevated serum calcium, low serum phosphate, achlorhydria, or suspected digoxin toxicity.
CaCO3 is a versatile mineral with different applications such as construction (limestone), bone cements, dental implants, drug delivery and pharmaceutical use in oral formulations as an excipient/active substance.
CaCO3 nanoparticles have exhibited promising potential as drug carriers targeting cancer tissues and cells.