High biocompatibility- CaCO3 is also employed in many pharmaceutical (anti-acid, dietary supplement for child and postmenopausal women), biological (scaffolds for cellular and bacterial growth) and biomedical (bioactive material for drug delivery, base for orthodontic cements) applications.
CaCO3 nanoparticles have attracted an interest among researchers nowadays especially for therapeutic applications.
Calcium carbonate based material present the biodegradability and biocompatibility properties which is ideal as a smart carrier to deliver genes, enzymes, and drugs.
Calcium carbonate nanoparticles have been observed to be biocompatible for use in medicine, pharmaceutical industries and drug delivery systems
Calcium carbonate use is contraindicated in cases of hypersensitivity, renal calculus, high urine calcium levels, elevated serum calcium, low serum phosphate, achlorhydria, or suspected digoxin toxicity.
CaCO3 is a versatile mineral with different applications such as construction (limestone), bone cements, dental implants, drug delivery and pharmaceutical use in oral formulations as an excipient/active substance.
CaCO3 nanoparticles have exhibited promising potential as drug carriers targeting cancer tissues and cells.